OPPORTUNITIES OF FLOW CYTOMETRY IN DIAGNOSTICS OF INFECTIOUS DISEASES. PART 1

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  • Authors: Khaidukov S.V.1, Zurochka A.V.2
  • Affiliations:
    1. Институт биоорганической химии им. акад. М.М. Шемякина и Ю.А. Овчинникова РАН, Москва ФГУ Федеральный Научно-Клинический Центр детской гематологии, онкологии и иммунологии РОСЗДРАВА, Москва
    2. Институт иммунологии и физиологии УрО РАН, г. Екатеринбург
  • Issue: Vol 1, No 1 (2011)
  • Pages: 59-66
  • Section: REVIEWS
  • URL: https://iimmun.ru/iimm/article/view/28
  • DOI: https://doi.org/10.15789/2220-7619-2011-1-59-66
  • ID: 28


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Abstract

Abstract. Development of a modern medical science demands more thorough and deeper approach to diagnostics of diseases. New diagnostic technologies for these investigations are necessary and flow cytometry is such technology. Modern achievements in the field of fluorescent dyes, development of laser and computer technologies, have led to wide use of the given technology in medical practice. Infectious immunology is not exception. Cytokines production analysis at tuberculosis, HLA-DR expression changes for monocytes and CD64 for granulocytes at sepsis are the important diagnostic attributes. Flow cytometry offers new approaches to early and faster diagnostics of infringements of immune system at tuberculosis and sepsis, allows supervising development of these pathologies more effectively and estimate efficiency of therapy.

About the authors

S. V. Khaidukov

Институт биоорганической химии им. акад. М.М. Шемякина и Ю.А. Овчинникова РАН, Москва

ФГУ Федеральный Научно-Клинический Центр детской гематологии, онкологии и иммунологии РОСЗДРАВА, Москва

Author for correspondence.
Email: khsv@mail.ibch.ru

д.б.н., зав. лабораторией физиологии и патологии иммунной системы

117997, Москва, ул. Миклухо-Маклая, 16/10

Russian Federation

A. V. Zurochka

Институт иммунологии и физиологии УрО РАН, г. Екатеринбург

Email: khsv@mail.ibch.ru
Russian Federation

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